Digit Ratio (2D:4D) and cancer: What is known so far?

Renato Nicolás Hopp, Nathalia Caroline Souza Lima, José Laurentino Ferreira Filho, Marcondes Sena-Filho, Renata Oliveira Samuel, Jackeline Gallo Amaral, Jacks Jorge


The ratio between the second and fourth digits is a proxy marker for prenatal exposure and sensitivity to sexual hormones, which can be genetically influenced. The influence of prenatal hormone exposure can reflect on adult life traits such as psychological traits, athletic performance and diseases such as cardiovascular. An important and newly explored field on digit ratio research is its correlation to different types of cancer, as a marker for prevalence and severity. In this review, the different types of cancer already correlated to digit ratios are discussed.


Cite this article as: Hopp RN, Lima N, Filho J, Sena-Filho M, Samuel RO, Amaral JG, Jorge J. Digit Ratio (2D:4D) and cancer: What is known so far? Int J Cancer Ther Oncol 2014; 2(1):020111.

DOI: http://dx.doi.org/10.14319/ijcto.0201.11


Prenatal testosterone; Digit ratio; Cancer

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DOI: http://dx.doi.org/10.14319/ijcto.0201.11

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