Relapse of unusual localization of classic seminoma with post-chemotherapy transformation

Mayte Delgado Ureña, Marta Legerén, Fernando Gálvez, Ana Villaescusa, Jorge Aparicio, Jose M Jurado, Isabel Blancas, Maria Sánchez, Ana L Romera, Ana P Martínez, Enoe Quiñonez, Isabel Dulcey, Jose L Puche


Germ cell tumor is the most common cancer among males in the 20–39 year-old age range, representing 21% of invasive cancer diagnose. The vast majority of testicular tumors in this age range are germ cell tumors. There are two types of malignant tumors, the pure seminoma cell and non-seminomatous germinal cell tumors (NGCT). We present the case of a patient who underwent a testicular tumor surgery, classic seminoma stage I, receiving two cycles of adjuvant carboplatin chemotherapy. During the follow up, an elevation on the alpha-fetoprotein level was observed, thus the final diagnosis was adenopatic recurrence of the Yolk Sac tumor.


Cite this article as: Urena MD, Legeren M, Galvez F, Villaescusa A, Aparicio J, Jurado JM, Blancas I, Sanchez MJ, Romera AL, Martinez AP, Quiñonez E, Dulcey I, Puche JL. Relapse of unusual localization of classic seminoma with post-chemotherapy transformation. Int J Cancer Ther Oncol 2014; 2(1):02016.



Classic Seminoma; Alpha-fetoprotein; Vitelline tumor

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International Journal of Cancer Therapy and Oncology (ISSN 2330-4049)

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