Radiotherapy for large cutaneous angiosarcoma of face with RapidArc (VMAT)

Mirza Athar Ali, Babaiah Muntimadugu, Madhusudhan Nagaraju, Sujana Vuba, Geomcy George, KR Muralidhar, Birendra Rout, Prabhakar Mariappan

Abstract


Angiosarcoma is a rare malignancy of vascular origin. It can affect any part of the body, head and neck region being probably the most common site of diagnosis. We present here a case of Angiosarcoma of face in a 67-year-old elderly gentleman who was treated with RapidArc – volumetric modulated arc therapy (VMAT) for recurrence after surgery, radiotherapy and chemotherapy. As an alternative to Electron Beam Therapy, RapidArc with skin bolus can be considered for large complex shaped targets with irregular surface and tissue inhomogeneity. RapidArc plan can achieve adequate target coverage with acceptable dose homogeneity and conformity.


Keywords


RapidArc; Cutaneous Angiosarcoma

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References


Stewart FW, Treves N. Lymphangiosarcoma in post-mastectomy lymphedema: a report of six cases in elephantiasis chirurgica. Cancer 1948; 1:64-81.

Antonescu C. Malignant vascular tumors - An update. Modern Pathology 2014; 27: S30-8.

Miettinen M, Lindenmayer AE, Chaubal A. Endothelial cell markers CD31, CD34 and BHN-9, antibody to H- and Y-antigens - evaluation of their specificity and sensitivity in the diagnosis of vascular tumors and comparison with von Willebrand factor. Mod Pathol 1994; 7:82-90.

Folpe AL, Chand EM, Goldblum JR, Weiss SW. Expression of Fli-1, a nuclear transcription factor, distinguishes vascular neoplasms from potential mimics. Am J Surg Pathol 2001; 25:1061-6.

Khan FM, Doppke KP, Hogstrom KR, et al. Clinical electron-beam dosimetry: report of AAPM Radiation Therapy Committee Task Group No. 25. Med Phys 1991; 18:73-109.

Ali MA, Babaiah M, Madhusudhan N, George G, Jain S, Ramalingam K, Kumar SA, Karthikeyan K, Anantharaman A . Comparative dosimetric analysis of IMRT and VMAT (RapidArc) in brain, head and neck, breast and prostate malignancies. Int J Cancer Ther Oncol 2015; 3: 03019.

Rout BK, Muralidhar KR, Ali M, Shekar MC, Kumar A. Dosimetric study of RapidArc plans with flattened beam (FB) and flattening filter-free (FFF) beam for localized prostate cancer based on physical indices. Int J Cancer Ther Oncol 2014; 2:02046.

Rana S, Pokharel S, Zheng Y, Zhao L, Risalvato D, Vargas C, Cersonsky N. Treatment planning study comparing proton therapy, RapidArc and intensity modulated radiation therapy for a synchronous bilateral lung cancer case. Int J Cancer Ther Oncol 2014; 2:020216.

Zacarias AS, Brown MF, Mills MD. Volumetric modulated Arc therapy (VMAT) treatment planning for superficial tumors. Med Dosim 2010; 35:226-9.

Collins SP, Coppa ND, Zhang Y, et al. Cyberknife radiosurgery in the treatment of complex skull base tumours: analysis of treatment planning parameters. Radiat Oncol 2006; 1:46.

Feuvret L, Noël G, Mazeron JJ, Bey P. Conformity index: a review. Int J Radiat Oncol Biol Phys 2006; 64:333-42.




DOI: http://dx.doi.org/10.14319/ijcto.0302.3

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International Journal of Cancer Therapy and Oncology (ISSN 2330-4049)

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