Imatinib in PDGFR positive malignant solitary fibrous tumour of the pleura

Sarah Bigeni, Cynthia Jones, Joseph Galea


In 2013, two cases of malignant solitary fibrous tumours (MSFTs) were diagnosed in Malta. Both were inoperable at presentation. Both tumours expressed platelet-derived growth factor receptor (PDGFR) with no mutations and the tyrosine kinase inhibitor imatinib was prescribed. Nonetheless, treatment was not as effective as documented in previous case-reports.


Malignant Solitary Fibrous Tumours, Imatinib, Pleura, PDGFR

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International Journal of Cancer Therapy and Oncology (ISSN 2330-4049)

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